Examples:

• If you want to invest in the stock market, it's ok. Gambling, however, is a horse of a different color.
• This project is a horse of a different color, it's much more complex than anything we've done before.
• She's a horse of a different color, she's not like any other woman I've dated.
• He's a horse of a different color, he's not like any other politician I've seen.
• This investment is a horse of a different color, it's much riskier than anything we've considered before.
• This issue is a horse of a different color, it's not like any other problem we've faced.
• This proposal is a horse of a different color, it's much more ambitious than anything we've seen before.
• This situation is a horse of a different color, it's not like any other challenge we've faced.
• This opportunity is a horse of a different color, it's much more exciting than anything we've had before.
• This crisis is a horse of a different color, it's not like any other emergency we've had to deal with.
• This new technology is a horse of a different color, it's not like anything we've seen before.
• This new business model is a horse of a different color, it's not like any other we've tried before.
• This new approach is a horse of a different color, it's not like any other method we've used before.
• This new idea is a horse of a different color, it's not like any other concept we've considered before.
• This new product is a horse of a different color, it's not like any other we've developed before.
• This new plan is a horse of a different color, it's not like any other strategy we've adopted before.