Examples:

• What is it you have in that belly, a worm?
• What is it you want, in one sentence or less?
• What is it that determines the course of our lives?
• What is it that makes you so drawn to her?
• What is it that you want on a silver platter?
• What is it that you feel so compelled to say?
• What is it with this place and all these rules?
• What is it exactly that you have against my friends?
• What is it, now that France has lost the war?
• What is it that Lex was so close to finding?