Meaning:
When some kind of unexpected issue shows up, someone might use the phrase “Houston, we have a problem” to indicate as much.
Examples:
- Houston, we have a problem: the stars all have tummy aches!
- I want to start off by saying, Houston, we have a problem.
- Oh, is this, like, a "Houston, we have a problem" situation?
- Houston, we have a problem.
- Houston, we have a problem.
- Uh... Houston, we have a problem.
- Houston, we have a problem.
- Wait, Houston, we have a problem.
- DOOR OPENS Houston, we have a problem.
- Houston, we have a problem. That's not mine.